マテリアル インテグレーション 2011年7月号
特集　進化と深化をはじめた機能性食品の世界(1)

北海道立総合研究機構の設立と新たな展開
■著者
地方独立行政法人　北海道立総合研究機構 理事長 丹保　憲仁

■要約
道総研では,基礎的な研究や調査等を行う「経常研究」や,実用化を目指した「重点研究」,分野横断型の課題に対応した「戦略研究」をはじめ,民間企業と連携した「共同研究」及び「受託研究」などを実施している.本稿では,単独の研究機関では解決が難しい,複数の分野にまたがり川上から川下までを視野に入れ,研究資源を重点化して取り組む研究として「戦略研究」を紹介する.


乳酸菌HOKKAIDO株を用いた機能性を有する食品の開発
■著者
地方独立行政法人　北海道立総合研究機構　産業技術研究本部食品加工研究センター　食品バイオグループ 中川　良二

■要約
漬物から分離された乳酸菌Lactobacillus plantarum HOKAKIDO (HOKKAIDO株) は,消化液耐性,細胞付着性および免疫調節作用等の機能性が示唆され,新たな北海道ブランドの乳酸株として発酵豆乳や特徴ある野菜ジュースなどの食品開発に利用されています.


北海道米の機能性を探る
■著者
地方独立行政法人　北海道立総合研究機構　農業研究本部上川農業試験場　生産環境グループ 柳原　哲司

■要約
近年は食味評価の高い北海道米であるが,機能性という視点から評価しても大きな潜在力を秘めている.米アレルギー患者に求められ続ける米「ゆきひかり」や難消化性成分の機能性に関する研究するとともに,北海道米の機能性を活かした販売戦略について考察する.


機能性食品としての大豆栽培〜イソフラボン含有量における北海道の優位性と高イソフラボン新品種〜
■著者
地方独立行政法人　北海道立総合研究機構　農業研究本部十勝農業試験場　生産環境グループ 谷藤　健

■要約
がん予防等に効果がある機能性成分として注目される大豆イソフラボンに関しては,大豆の栽培段階における特性も研究が進み,特に,登熟中の低温環境が含有量を高めることが明らかにされてきた.他地域に比べ登熟温度が低い北海道はこの点において優位性を持つことが確認されたほか,近年は北海道の栽培環境に適した高イソフラボン新品種「ゆきぴりか」が開発され,さらなる高含量が実現したことから,これらの取り組みについて概要を紹介する.


さっぽろバイオクラスター構想``Bio-Sの取り組み
■著者
公益財団法人　北海道科学技術総合振興センター　 知的クラスター本部　事業総括　 鈴木　文夫

■要約
Our goal at Bio-S is to implement, through the power of internationally competitive science, the establishment of a foundation that will allow health sciences industries to take root in Hokkaido.Since its launch in 2007, the Bio-S project has promoted research on characteristic functional evaluation in the three fields of metabolic, immune and cognitive function, which deteriorates with age and lifestyle changes. It has promoted the evaluation of various food and food ingredients and made progress in efforts to identify biomarkers that indicate related disease processes. All our projects have been managed by the following strategies under collaboration between universities and industries.Business strategy: 1) Exploring project = Discovery of biomarkers, 2) Development project = Development of functional foods, 3) Evaluation project = Development of diagnostic & test kits and building the business center for functional evaluation.R & D strategy: 1. Pursuing scientific innovation, 2. Pursuing commercialization or academic promotion, 3. Building research hubs for food innovation.Globalization strategy: Building the Sapporo-based R & D hub of functional foods for East Asia and pursuing extensively complementary alliance.Human resource development strategy: Development of food science adviser versed in Hokkaido health foods and clinical research coordinators for functional foods in Bio-S Food Science College.


抗酸化機能分析研究センター構築とその取り組み
■著者
旭川医科大学医学部微生物学講座 若宮　伸隆

■要約
Anti-oxidant activity is defined as the value of oxygen radical activity suppression. Many reports suggest that oxygen radicals are able to cause cancer and quicken aging and metabolic syndromes. In general, scientists suppose that food materials containing anti-oxidant activity inhibit injury by oxygen radicals, therefore having an effective role in the prevention and therapy against diseases.``The Research Center of Anti-Oxidant Activity Analyses" was established as a part of the Bio-S project in Asahikawa Medical University to evaluate anti-oxidant activity in Hokkaido's plants and natural products. The center is utilized as an analysis center, for the promotion and development of Hokkaido Food Industry and Science. The center has made a data base from the analytical results and a sample library of polyphenol antioxidant materials, and information from the center will be released not only in Hokkaido, but in Japan and to the entire world. Since 2009, we have mainly focused on analyzing the polyphenol antioxidants in berries for wine and beans that are cultivated in Hokkaido. By 2011, we have a plan to complete the anti-oxidant activity data base and sample library for 500-600 of Hokkaido's plants which covers much of the food eaten in the area.


ユニークな分析技術に基づく高度脂質分析ラボの構築
■著者
北海道大学保健学研究院 教授 千葉　仁志

■要約
Development of new testing methods for lipids and lipoproteins useful in prevention and treatment of lipid-related diseases is in progress in our laboratory, such as carbon nanotube sensor and monoclonal antibody for oxidized LDL, atomic-force microscope for lipoprotein particle sizes, and quantitative lipidomics for lipid peroxides and plasmalogens. On the basis of these unique technologies, we are constructing advanced lipid laboratory, which would provide analytical services to companies and researchers, commercial kits for lipid measurements, and also data interpretation and consultation services. This laboratory might be linked with similar laboratories in Japan and foreign countries and start joint business with them. To support this laboratory, funding from the government and companies is necessary. There should be a COE (center of excellence) program for higher lipid studies beside the advanced lipid laboratory, which will help the lab keep being the forerunner and provide human resource. (144 words)


食材の臨床試験とその拠点作り
■著者
北海道情報大学医療情報学科 教授 西平　順

■要約
``Food and Health" is the major theme of the current research-oriented project, Knowledge Cluster Initiatives, Sapporo Bio-S. This project is uniquely designed to apply science-based outcomes of functional foods for the promotion of food business in Hokkaido. With cooperative work by all members, not only in agricultural and marine businesses, but also in the fields of medicine and nutrition, the goal is set to raise market values of agricultural and marine products originating in Hokkaido. To complete this goal, we have established the ``Clinical Trial System" in Ebetsu City located in central Hokkaido to evaluate the safety and functions of foods for human health. The system provides cost-effective and highly-qualified medical service. It is highly expected that this system will enhance the development of food science and economic activities in Hokkaido.


高齢社会の課題解決研究フィールドを目指するもいコホートピアの取り組み
■著者
札幌医科大学医学部フロンティア医学研究所病態情報学分野 教授 小海　康夫

■要約
Many developed countries face a rapid increase of aged people. The speed of aging is more than expected or scheduled, raising many issues in our life. On the other hand, rapid increase of aging people parallels decrease of new born babies, which results in decrease of working people and over all habitancy. Japan has become a leading country for the number of aged people and keeps the top rank of longest generation in the world. This directly links to the reduction of production of heavy industrial products and has suggested paradigm shift from old industrial country to a new style with sustainable life style. Since Japan is a leader for aging country, we have to solve issues in aging society by ourselves. We are requested for the solution in aging life, meaning that we have become a top runner in this particular situation. Many matters in the actual life have been optimized for virile ages and have hampered a sustainable life for aged people. Nonetheless, we have to change structures of our society for aged people. The issues with aged people may be a target for the innovation or, in other words, a new paradigm for the near future of human being. We have being trying to establish open field for geriatric science in Rumoi city, Hokkaido. In this brief paper, we introduce you a summary of our activity in Rumoi city. The concepts of Rumoi Cohortopia, a pet name of this activity, are1. Open filed for research in any field dealing with health.\\2. Local members of Rumoi Cohortopia guide to facilitate research in the City.3. Visit of Rumoi City to learn about ``what is Rumoi Cohortopia" is just welcome.


函館マリンバイオクラスター形成への取り組み
■著者
公益社団法人函館地域産業振興財団　副理事長・北海道立工業施術センター長　函館マリンバイオクラスター　事業総括 三浦　汀介

■要約
Natural, geographical, and historical advantages for fisheries and marine industries have collected various industries and prominent scientific institutions in the Hakodate area. Based on this character, the 'Hakodate International Fisheries and Ocean City Concept' commenced in 2003, in which the formation of an international scientific research city of fisheries and marine science was targeted. A number of projects developing scientific technologies into industrial advancement have since been implemented. Currently, we have a platform of industry-academia-government collaboration. To optimally exploit this foundation, we aim to form a sustainable marine bio industrial cluster through the global innovation of fisheries and marine science. In this innovation, we recognize the ocean as a huge and measurable production system, and develop total technologies in order to utilize valuable substances from marine bio-resources.In this project, we have the following four research-and-development themes:1. Improvement of the balance between an advanced use and sustainable use of biota and aquatic environment in the coastal region using marine spatial information 2. Autonomous' green bio-farming' of the northern mega-benthos containing high value added products 3. Research and development for creation of highly functional resources harnessing biological characteristics of mega-benthos 4. Research and development for establishment of global standards for food quality and health effects


とかちABCプロジェクトの概要
■著者
帯広畜産大学　特任教授　とかちABCプロジェクト　事業総括 伊藤　繁

■要約


解説
ガラスに出会う-古代鉛ガラスの東遷(2)
■著者
寺井ガラス技術事務所 寺井　良平

■要約


連載
タイ便り(48) 籾殻発電の現状と将来
■著者
和田　重孝

■要約
世界的に見れば,バイオマス全体の中で“籾殻”はさほど大きな割合を占めないであろう.世界全体で見れば,木材チップやバガスが多い.ただし,東南アジアは先の1億トンの籾殻の大部分を排出するから,東南アジアにおいて籾殻は重要なバイオマスである.筆者は籾殻の利用に関して興味を持ってきたので,発電燃料としての籾殻の課題について考えてみたい.


連載
近代日本のセラミックス産業と科学・技術の発展に尽力した偉人,怪人,異能,努力の人々(44)
■著者
宗宮 重行

■要約