PDF/月刊誌論文/code:pg_1104_04 マテリアル インテグレーション 2011年4月号
MATERIALS INTEGRATION 地域と世界に貢献する東北大学多元物質科学研究所(4,5月合併号)

生命現象の機能解明・制御ツールとしての人工核酸・タンパク質創製と生体分子構造変化の高時間分解検出法の開発
■著者
東北大学多元物質科学研究所 有機・生命科学研究部門　生命機能制御物質化学研究分野 和田 健彦

■要約
A chemical synthesis and modification of DNA/RNA is the fundamental technology that has led the molecular biology revolution. Hence, a chemistry of DNA and RNA not only in vitro but also in vivo expects to open new generational stage of bioorganic chemistry and molecular biology. Thus, focusing our research interest mostly on the recognition and complexation behavior control of biopolymers, such as DNA/RNA, proteins by external factors, toward the active control of cellular functions. Another topics are reaction control based on molecular recognition phenomena in both ground and electronically excited states; we are pursuing mechanistic and synthetic studies on asymmetric photochemistry with supramolecular biopolymers as chiral reaction fields.